Alternative Sources of n-3 Long-Chain Polyunsaturated Fatty Acids in Marine Microalgae
Open Access
- 27 June 2013
- journal article
- review article
- Published by MDPI AG in Marine Drugs
- Vol. 11 (7), 2259-2281
- https://doi.org/10.3390/md11072259
Abstract
The main source of n-3 long-chain polyunsaturated fatty acids (LC-PUFA) in human nutrition is currently seafood, especially oily fish. Nonetheless, due to cultural or individual preferences, convenience, geographic location, or awareness of risks associated to fatty fish consumption, the intake of fatty fish is far from supplying the recommended dietary levels. The end result observed in most western countries is not only a low supply of n-3 LC-PUFA, but also an unbalance towards the intake of n-6 fatty acids, resulting mostly from the consumption of vegetable oils. Awareness of the benefits of LC-PUFA in human health has led to the use of fish oils as food supplements. However, there is a need to explore alternatives sources of LC-PUFA, especially those of microbial origin. Microalgae species with potential to accumulate lipids in high amounts and to present elevated levels of n-3 LC-PUFA are known in marine phytoplankton. This review focuses on sources of n-3 LC-PUFA, namely eicosapentaenoic and docosahexaenoic acids, in marine microalgae, as alternatives to fish oils. Based on current literature, examples of marketed products and potentially new species for commercial exploitation are presented.Keywords
This publication has 126 references indexed in Scilit:
- Best practices in heterotrophic high-cell-density microalgal processes: achievements, potential and possible limitationsApplied Microbiology and Biotechnology, 2011
- Major Dietary Protein Sources and Risk of Coronary Heart Disease in WomenCirculation, 2010
- Microbial production of docosahexaenoic acid by a low temperature‐adaptive strain Thraustochytriidae sp. Z105: screening and optimizationJournal of Basic Microbiology, 2010
- Blood Eicosapentaenoic and Docosahexaenoic Acids Predict All-Cause Mortality in Patients With Stable Coronary Heart DiseaseCirculation: Cardiovascular Quality and Outcomes, 2010
- Microalgae for biodiesel production and other applications: A reviewRenewable and Sustainable Energy Reviews, 2010
- Polyunsaturated fatty acids and inflammatory processes: New twists in an old taleBiochimie, 2009
- Microalgal triacylglycerols as feedstocks for biofuel production: perspectives and advancesThe Plant Journal, 2008
- Fish Intake, Contaminants, and Human HealthJAMA, 2006
- Isolation of enhanced eicosapentaenoic acid producing mutants of Nannochloropsis oculata ST‐6 using ethyl methane sulfonate induced mutagenesis techniques and their characterization at mRNA transcript levelPhycological Research, 2006
- A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONCanadian Journal of Biochemistry and Physiology, 1959