Risk Factors for Falls in Community-dwelling Older People
Top Cited Papers
- 1 September 2010
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Epidemiology
- Vol. 21 (5), 658-668
- https://doi.org/10.1097/ede.0b013e3181e89905
Abstract
Falls are the main cause of accidental death in persons aged 65 years or older. Using MEDLINE and previous reviews, we searched for prospective studies investigating risk factors for falls among community-dwelling older people. For risk factors investigated by at least 5 studies in a comparable way, we computed pooled odds ratios (ORs) using random-effects models, with a test for heterogeneity. A total of 74 studies met the inclusion criteria and 31 risk factors were considered, including sociodemographic, mobility, sensory, psychologic, and medical factors and medication use. The strongest associations were found for history of falls (OR = 2.8 for all fallers; OR = 3.5 for recurrent fallers), gait problems (OR = 2.1; 2.2), walking aids use (OR = 2.2; 3.1), vertigo (OR = 1.8; 2.3), Parkinson disease (OR = 2.7; 2.8), and antiepileptic drug use (OR = 1.9; 2.7). For most other factors, the ORs were moderately above 1. ORs were generally higher for recurrent fallers than for all fallers. For some factors, there was substantial heterogeneity among studies. For some important factors (eg, balance and muscle weakness), we did not compute a summary estimate because the measures used in various studies were not comparable. This meta-analysis provides comprehensive evidence-based assessment of risk factors for falls in older people, confirming their multifactorial etiology. Some nonspecific indicators of high baseline risk were also strong predictors of the risk of falling.Keywords
This publication has 88 references indexed in Scilit:
- Biomarkers of aging and falling: The Beaver Dam eye studyArchives of Gerontology and Geriatrics, 2009
- Falls risk among a very old home-dwelling populationScandinavian Journal of Primary Health Care, 2009
- Additive benefit of higher testosterone levels and vitamin D plus calcium supplementation in regard to fall risk reduction among older men and womenOsteoporosis International, 2008
- Multidimensional Geriatric Assessment: Back to the Future Preclinical Disability as a Risk Factor for Falls in Community-Dwelling Older AdultsThe Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 2008
- Can Echocardiographic Findings Predict Falls in Older Persons?PLOS ONE, 2007
- Frailty and Risk of Falls, Fracture, and Mortality in Older Women: The Study of Osteoporotic FracturesThe Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 2007
- Will My Patient Fall?JAMA, 2007
- An Age-Related Decrease in Creatinine Clearance Is Associated with an Increase in Number of Falls in Untreated Women But Not in Women Receiving Calcitriol TreatmentJournal of Clinical Endocrinology & Metabolism, 2007
- A risk profile for identifying community-dwelling elderly with a high risk of recurrent falling: results of a 3-year prospective studyOsteoporosis International, 2006
- Meta-analysis in clinical trialsControlled Clinical Trials, 1986