Clinical relevance of the ESKAPE pathogens
Top Cited Papers
- 1 March 2013
- journal article
- review article
- Published by Informa UK Limited in Expert Review of Anti-infective Therapy
- Vol. 11 (3), 297-308
- https://doi.org/10.1586/eri.13.12
Abstract
In recent years, the Infectious Diseases Society of America has highlighted a faction of antibiotic-resistant bacteria (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter spp.) - acronymically dubbed 'the ESKAPE pathogens' - capable of 'escaping' the biocidal action of antibiotics and mutually representing new paradigms in pathogenesis, transmission and resistance. This review aims to consolidate clinically relevant background information on the ESKAPE pathogens and provide a contemporary summary of bacterial resistance, alongside pertinent microbiological considerations necessary to face the mounting threat of antimicrobial resistance.Keywords
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