Mechanisms of Metal Resistance and Homeostasis in Haloarchaea
Open Access
- 21 February 2013
- journal article
- review article
- Published by Hindawi Limited in Archaea
- Vol. 2013, 1-16
- https://doi.org/10.1155/2013/732864
Abstract
Haloarchaea are the predominant microflora of hypersaline econiches such as solar salterns, soda lakes, and estuaries where the salinity ranges from 35 to 400 ppt. Econiches like estuaries and solar crystallizer ponds may contain high concentrations of metals since they serve as ecological sinks for metal pollution and also as effective traps for river borne metals. The availability of metals in these econiches is determined by the type of metal complexes formed and the solubility of the metal species at such high salinity. Haloarchaea have developed specialized mechanisms for the uptake of metals required for various key physiological processes and are not readily available at high salinity, beside evolving resistance mechanisms for metals with high solubility. The present paper seeks to give an overview of the main molecular mechanisms involved in metal tolerance in haloarchaea and focuses on factors such as salinity and metal speciation that affect the bioavailability of metals to haloarchaea. Global transcriptomic analysis during metal stress in these organisms will help in determining the various factors differentially regulated and essential for metal physiology.Keywords
Funding Information
- Ministry of Earth Sciences (MoES/11-MRDF/1/38/P/10-PC-III)
This publication has 157 references indexed in Scilit:
- The information transfer system of halophilic archaeaPlasmid, 2011
- The transport mechanism of bacterial Cu+-ATPases: distinct efflux rates adapted to different functionBioMetals, 2011
- Haloferax volcanii Flagella Are Required for Motility but Are Not Involved in PibD-Dependent Surface AdhesionJournal of Bacteriology, 2010
- Coordination Chemistry of Bacterial Metal Transport and SensingChemical Reviews, 2009
- Functional and Expression Analyses of the cop Operon, Required for Copper Resistance in Agrobacterium tumefaciensJournal of Bacteriology, 2009
- Response to excess copper in the hyperthermophile Sulfolobus solfataricus strain 98/2Biochemical and Biophysical Research Communications, 2009
- Global Transcript Levels Respond to Small Changes of the Carbon Status during Progressive Exhaustion of Carbohydrates in Arabidopsis RosettesPlant Physiology, 2008
- A systems view of haloarchaeal strategies to withstand stress from transition metalsGenome Research, 2006
- Free radicals, metals and antioxidants in oxidative stress-induced cancerChemico-Biological Interactions, 2006
- Acquisition of siderophores in Gram-negative bacteriaNature Reviews Molecular Cell Biology, 2003