Mdm2 Is Required for Survival of Hematopoietic Stem Cells/Progenitors via Dampening of ROS-Induced p53 Activity
- 5 November 2010
- journal article
- Published by Elsevier BV in Cell Stem Cell
- Vol. 7 (5), 606-617
- https://doi.org/10.1016/j.stem.2010.09.013
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- p53-dependent senescence delays Eμ-myc-induced B-cell lymphomagenesisOncogene, 2009
- p53 Regulates Hematopoietic Stem Cell QuiescenceCell Stem Cell, 2009
- The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseasesBlood, 2008
- Hematopoiesis: An Evolving Paradigm for Stem Cell BiologyCell, 2008
- A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic nicheBlood, 2007
- Haploinsufficiency of Mdm2 and Mdm4 in Tumorigenesis and DevelopmentMolecular and Cellular Biology, 2007
- Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53‐dependent cellular senescenceEMBO Reports, 2007
- Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defectJCI Insight, 2006
- Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptorsBlood, 2006
- The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotypeImmunity, 1994