Regional Cerebral Glucose Metabolism of Women With Trichotillomania
- 1 September 1991
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 48 (9), 828-833
- https://doi.org/10.1001/archpsyc.1991.01810330052008
Abstract
• Positron emission tomography and 18-F-fluorodeoxyglucose were used to study resting cerebral glucose metabolism in 10 adult women with trichotillomania and 20 agematched female controls. As a group, the patients with trichotillomania showed significantly increased global (mean gray matter) and normalized right and left cerebellar and right superior parietal glucose metabolic rates. Contrary to expectation, this pattern differed from that seen in our previous investigation of obsessive-compulsive disorder. Clomipramine hydrochloride—induced improvement was negatively correlated with anterior cingulate and orbital frontal metabolism, of particular interest because similar results had been obtained for obsessive-compulsive disorder.This publication has 13 references indexed in Scilit:
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