An eosinophilotactic factor derived from rat mast cells
- 1 February 1975
- journal article
- Published by Wiley in The Journal of Pathology
- Vol. 115 (2), 91-96
- https://doi.org/10.1002/path.1711150205
Abstract
Rat eosinophils have been showed to respond chemotactically to the supernatant from mast cells which have been disrupted by freezing and thawing and from mast cells which have been specifically degranulated by Compound 48/80 or by antigen challenge or sensitised cells. The fact that the chemotactic response is not dependent on allergic degranulation suggests that the chemotactic factor is present pre-formed in the mast cells rather than being generated in response to an antigen-antibody reaction.Keywords
This publication has 3 references indexed in Scilit:
- The release of spasmogenic substances from human chopped lung tissue and its inhibitionBritish Journal of Pharmacology, 1973
- AN EOSINOPHIL LEUKOCYTE CHEMOTACTIC FACTOR OF ANAPHYLAXISThe Journal of Experimental Medicine, 1971
- An electron-microscope study of the relations between mast cells and eosinophil leucocyteThe Journal of Pathology, 1969