Prospective Study of Alcohol Consumption and Cancer
- 8 March 1984
- journal article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 310 (10), 617-621
- https://doi.org/10.1056/nejm198403083101003
Abstract
The relation between alcohol consumption and the subsequent occurrence of the five most frequent cancers in Japanese men in Hawaii (cancer of the stomach, colon, rectum, lung, and prostate) was analyzed in a prospective study of 8006 subjects. Information on alcohol consumption was obtained through interviews in the mid-1960s, and the cohort has been followed since then. The analysis, which was adjusted for the effects of age and cigarette smoking, revealed a positive association between consumption of alcohol and rectal cancer, accounted for primarily by an increased risk in men whose usual monthly consumption of beer was 500 oz (15 liters) or more (relative risk, 3.05; P<0.01, as compared with those who did not drink beer). A significant positive relation between alcohol consumption and lung-cancer incidence was also found, accounted for primarily by an increased risk among subjects who consumed larger amounts of wine or whiskey, as compared with the risks among nonconsumers of these beverages (relative risk, 2.19, [P = 0.03] and 2.62 [P<0.01], respectively). No significant relation between alcohol consumption and the incidence of the other three cancers was found. (N Engl J Med 1984; 310:617–21.)Keywords
This publication has 19 references indexed in Scilit:
- Stratified trend and homogeneity analyses of proportions and life table dataComputers and Biomedical Research, 1983
- The role of drinking and smoking in mortality from cancer and other causes in male alcoholicsCancer, 1981
- Causes of death of blue-collar workers at a Dublin brewery, 1954-73British Journal of Cancer, 1979
- Cancer morbidity and causes of death among danish brewery workersInternational Journal of Cancer, 1979
- Coffee, Alcohol and Risk of Coronary Heart Disease among Japanese Men Living in HawaiiThe New England Journal of Medicine, 1977
- Low-Fiber Intake as an Etiologic Factor in Cancer of the Colon 2JNCI Journal of the National Cancer Institute, 1975
- Ascertainment of men of Japanese ancestry in Hawaii through World War II Selective Service registrationJournal of Chronic Diseases, 1970
- Environmental factors of cancer of the colon and rectumII. Japanese epidemiological dataCancer, 1969
- Environmental factors of cancer of the colon and rectumCancer, 1967
- A study of etiological factors in cancer of the esophagusCancer, 1961