Use of anti‐neurofilament antibody to identify paired‐helical filaments in inclusion‐body myositis
- 1 March 1996
- journal article
- research article
- Published by Wiley in Annals of Neurology
- Vol. 39 (3), 389-391
- https://doi.org/10.1002/ana.410390318
Abstract
Paired‐helical filaments (PHFs) are an important diagnostic criterion of the inclusion‐body myositis (IBM) muscle biopsy; but, until now, their presence could be identified only by electronmicroscopy. In this report, we describe an easy immunocytochemical procedure, utilizing commercially available antibody, that enables reliable identification of muscle PHFs by light microscopy. This procedure greatly facilitates diagnosis of IBM.This publication has 6 references indexed in Scilit:
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