Directed Discovery of Agents Targeting the Met Tyrosine Kinase Domain by Virtual Screening
- 15 January 2009
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 52 (4), 943-951
- https://doi.org/10.1021/jm800791f
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinibProceedings of the National Academy of Sciences of the United States of America, 2007
- Epigenetically Controlled Fibroblast Growth Factor Receptor 2 Signaling Imposes on the RAS/BRAF/Mitogen-Activated Protein Kinase Pathway to Modulate Thyroid Cancer ProgressionCancer Research, 2007
- FGFR1 amplification in breast carcinomas: a chromogenic in situhybridisation analysisBreast Cancer Research, 2007
- BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinitiesNucleic Acids Research, 2006
- Virtual screening of chemical librariesNature, 2004
- The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variantsOncogene, 2004
- Crystal Structure of Bisphosphorylated IGF-1 Receptor Kinase: Insight into Domain Movements upon Kinase ActivationStructure, 2001
- ATP site-directed competitive and irreversible inhibitors of protein kinasesMedicinal Research Reviews, 2000
- Development and validation of a genetic algorithm for flexible dockingJournal of Molecular Biology, 1997
- Automatic generation of 3D-atomic coordinates for organic moleculesTetrahedron Computer Methodology, 1990