Optogenetic experimentation on astrocytes
- 15 December 2010
- journal article
- review article
- Published by Wiley in Experimental Physiology
- Vol. 96 (1), 40-50
- https://doi.org/10.1113/expphysiol.2010.052597
Abstract
We briefly review the current literature where optogenetics has been used to study various aspects of astrocyte physiology in vitro and in vivo. This includes both genetically engineered Ca(2+) sensors and effector proteins, such as channelrhodopsin. We demonstrate how the ability to target astrocytes with cell-specific viral vectors to express optogenetic constructs helped to unravel some previously unsuspected roles of these inconspicuous cells.Keywords
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