Increased epicardial adipose tissue volume in HIV-infected men and relationships to body composition and metabolic parameters
- 24 August 2010
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in AIDS
- Vol. 24 (13), 2127-2130
- https://doi.org/10.1097/qad.0b013e32833c055a
Abstract
Epicardial fat accumulation may have important clinical consequences, yet little is known regarding this depot in HIV patients. We compared epicardial fat volume in 78 HIV-infected men and 32 HIV-negative controls. Epicardial fat volume was higher in HIV-infected patients than that in controls (P = 0.04). In HIV patients, epicardial fat volume was strongly associated with visceral adipose tissue area (ρ = 0.76, P < 0.0001), fasting glucose (ρ = 0.41, P = 0.001) and insulin (ρ = 0.44, P = 0.0003). Relationships with glucose and insulin remained significant controlling for age, race, BMI, adiponectin, visceral adipose tissue and antiretroviral therapy. Epicardial fat may be an important fat depot in HIV-infected patients.Keywords
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