The late phase of sepsis is characterized by an increased microbiological burden and death rate
Top Cited Papers
Open Access
- 1 January 2011
- journal article
- Published by Springer Science and Business Media LLC in Critical Care
- Vol. 15 (4), R183
- https://doi.org/10.1186/cc10332
Abstract
Recent models capturing the pathophysiology of sepsis and ex-vivo data from patients are speculating about immunosuppression in the so-called late phase of sepsis. Clinical data regarding survival and microbiological burden are missing. The aim of this study was to determine the clinical significance of the 'late phase' of sepsis with respect to overall survival and occurrence of microbiological findings.Keywords
This publication has 27 references indexed in Scilit:
- Risk factors for negative blood cultures in adult medical inpatients – a retrospective analysisBMC Infectious Diseases, 2008
- Proinflammatory cytokines and sepsis syndrome: not enough, or too much of a good thing?Trends in Immunology, 2003
- 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions ConferenceCritical Care Medicine, 2003
- The Pathophysiology and Treatment of SepsisNew England Journal of Medicine, 2003
- Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care unitsCritical Care Medicine, 1998
- A Randomized Controlled Trial of Filgrastim as an Adjunct to Antibiotics for Treatment of Hospitalized Patients with Community‐Acquired PneumoniaThe Journal of Infectious Diseases, 1998
- Interferon gamma-1b in the treatment of compensatory anti-inflammatory response syndrome. A new approach: proof of principleArchives of Internal Medicine, 1997
- The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failureIntensive Care Medicine, 1996
- Sir Isaac Newton, sepsis, SIRS, and CARSCritical Care Medicine, 1996
- Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in SepsisSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1992