Central core disease: Ultrastructure of the sarcoplasmic reticulum and T‐tubules
- 1 February 1989
- journal article
- research article
- Published by Wiley in Muscle & Nerve
- Vol. 12 (2), 95-102
- https://doi.org/10.1002/mus.880120203
Abstract
The modified Golgi staining method was used to study the sarcoplasmic reticulum (SR) and t- tubules of skeletal muscle in central core disease. Significant pathological changes were documented in both of these organelles in seven patients. Pathological changes were seen in both core and non-core regions, with the abnormalities being greatest in the cores. In noncore regions, distortions in the normal anatomy were minor. In cores, there was much more significant distortion of the normal anatomy and also an increase in the amount of SR and number of t-tubules.Keywords
This publication has 14 references indexed in Scilit:
- Three‐dimensional architecture of sarcoplasmic reticulum and T‐system in human skeletal muscleThe Anatomical Record, 1987
- Is central core disease with structural core a fetal defect?Zeitschrift für Neurologie, 1984
- A modified Golgi black reaction method for light and electron microscopy.Journal of Histochemistry & Cytochemistry, 1982
- Central core disease: Study of a family with five affected generationsJournal of the Neurological Sciences, 1982
- Central core disease in one of identical twins.Journal of Neurology, Neurosurgery & Psychiatry, 1978
- Calcium release from the sarcoplasmic reticulumPhysiological Reviews, 1977
- CENTRAL CORE DISEASE OR NOT?Brain, 1973
- A sporadic case of central core diseaseJournal of the Neurological Sciences, 1970
- CENTRAL CORE DISEASE OF MUSCLE: CLINICAL, HISTOCHEMICAL AND ELECTRON MICROSCOPIC STUDIES OF AN AFFECTED MOTHER AND CHILDBrain, 1970
- CENTRAL CORE DISEASE—AN INVESTIGATION OF A RARE MUSCLE CELL ABNORMALITYBrain, 1961