The Association Between Obstructive Sleep Apnea and Hypertension by Race/Ethnicity in a Nationally Representative Sample
Open Access
- 10 June 2013
- journal article
- research article
- Published by Wiley in The Journal of Clinical Hypertension
- Vol. 15 (8), 593-599
- https://doi.org/10.1111/jch.12144
Abstract
The association between obstructive sleep apnea (OSA) and hypertension by race/ethnicity has not been well characterized in a national sample. Adult participants in the 2007–2008 National Health and Nutrition Examination Survey were reviewed by self‐report of sleep apnea diagnosis, snorting, gasping or stopping breathing during sleep, and snoring to derive whether OSA was probable (pOSA). Multivariable logistic regression determined whether pOSA predicted hypertension in the overall cohort, and by body mass index (BMI) group and ethno‐racial strata. pOSA predicted hypertension in several groups: (1) Within BMI strata, there was a significant association among overweight individuals [odds ratio [OR], 1.82; 95% confidence interval [CI], 1.26–2.62); (2) In race/ethnicity subgroups, the association was significant among Hispanic/Latinos (OR, 1.69; 95% CI, 1.13–2.53) and whites (OR, 1.40; 95% CI, 1.07–1.84); (3) In models stratified by both race/ethnicity and BMI, pOSA predicted hypertension among overweight black/African Americans (OR, 4.74; 95% CI, 1.86–12.03), overweight whites (OR, 1.65; 95% CI, 1.06–2.57), and obese Hispanic/Latino participants (OR, 2.01; 95% CI, 1.16–3.49). A simple, self‐report tool for OSA was strongly associated with hypertension, and may serve as a potential future opportunity for OSA diagnosis.Keywords
Funding Information
- NIH (T32HL07713-19)
- American Heart Association (12SDG9180007)
- National Heart, Lung, and Blood Institute (K23HL110216)
- National Institute for Environmental Health Sciences (R21ES022931)
- Institute for Translational Medicine and Therapeutics (UL1RR024134, RO1-OH009149)
This publication has 42 references indexed in Scilit:
- Rapid risk stratification for obstructive sleep apnea, based on snoring severity and body mass indexOtolaryngology -- Head and Neck Surgery, 2008
- The Epidemiology of Adult Obstructive Sleep ApneaProceedings of the American Thoracic Society, 2008
- Obesity and Obstructive Sleep Apnea: Pathogenic Mechanisms and Therapeutic ApproachesProceedings of the American Thoracic Society, 2008
- Prevalence, Awareness, Treatment, and Control of Hypertension Among United States Adults 1999–2004Hypertension, 2007
- Ethnicity and obstructive sleep apnoeaSleep Medicine Reviews, 2005
- Obstructive Sleep Apnea SyndromesSeminars in Respiratory and Critical Care Medicine, 2005
- Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7)Hypertension, 2003
- The PHQ-9Journal of General Internal Medicine, 2001
- Snoring as a risk factor for ischaemic heart disease and stroke in men.BMJ, 1987
- Snoring as a risk factor for disease: an epidemiological survey.BMJ, 1985