Published International Classification of Retinoblastoma (ICRB) Definitions Contain Inconsistencies—An Analysis of Impact
- 1 January 2009
- journal article
- Published by Taylor & Francis Ltd in Ophthalmic Genetics
- Vol. 30 (1), 40-44
- https://doi.org/10.1080/13816810802452168
Abstract
To determine the impact of subtle differences (most notably in their classification of group E eyes) in two published versions of the ICRB (Philadelphia and the Children's Hospital Los Angeles). Analysis of a series of 96 eyes with intra-ocular retinoblastoma. The disparate criteria of the 2 published ICRB schemas affected group assignment of 5.2% of the eyes (25% of the group E eyes). Discrepancies need to be reconciled to ensure accurate and uniform application of the ICRB.Keywords
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