Women with low-energy fracture should be investigated for osteoporosis
Open Access
- 1 January 2007
- journal article
- Published by Informa UK Limited in Acta Orthopaedica
- Vol. 78 (6), 813-821
- https://doi.org/10.1080/17453670710014608
Abstract
Treatment of osteoporosis is becoming more effective, but methods to identify patients who are most suitable for investigation and treatment are still being debated. Should any type of fracture have higher priority for investigation of osteoporosis than any other? Is the number of previous fractures useful information? We investigated 303 consecutive women patients between 55 and 75 years of age who had a newly diagnosed low-energy fracture. They answered a questionnaire on previous fractures which also dealt with risk factors. Bone mineral density (BMD) was measured at the hip, lumbar spine, and forearm. The distribution of fracture location was: distal forearm 56%, proximal humerus 12%, vertebra 18%, and hip 13%, all with similar age. Half of the subjects had had at least one previous fracture before the index fracture, 19% had had two previous fractures, and 6% had had three or more previous fractures. Patients with vertebral or hip fracture had lower BMD and had had more previous fractures than patients with forearm or humerus fractures. There was an inverse correlation between number of fractures and BMD. Osteoporosis was present in one-third of patients with forearm fracture, in one-half of those with hip or humerus fracture, and in two-thirds of those with vertebral fracture. Vertebral fractures were the strongest marker of low BMD and forearm fractures the weakest. The number of previous fractures is helpful information for finding the most osteoporotic patient in terms of severity. Investigation of osteoporosis therefore seems warranted in every woman between the ages of 55 and 75 with a recent low-energy fracture, with highest priority being given to those with vertebral, hip, or multiple fractures.Keywords
This publication has 33 references indexed in Scilit:
- At what hip fracture risk is it cost-effective to treat?Osteoporosis International, 2006
- Health-related quality of life after osteoporotic fracturesOsteoporosis International, 2004
- Bone Mineral Density Measurement and Treatment for Osteoporosis in Older Individuals With FracturesArchives of Internal Medicine, 2003
- Low Frequency of Treatment of Osteoporosis Among Postmenopausal Women Following a FractureArchives of Internal Medicine, 2003
- The Relationship Between Bone Density and Incident Vertebral Fracture in Men and WomenJournal of Bone and Mineral Research, 2002
- Risk Factors for Perimenopausal Fractures: A Prospective StudyOsteoporosis International, 2000
- Screening for osteoporosisBMJ, 1999
- Forearm Fractures as Predictors of Subsequent Osteoporotic FracturesOsteoporosis International, 1999
- Hip Fracture Prediction in Elderly Men and Women: Validation in the Rotterdam StudyJournal of Bone and Mineral Research, 1998
- Risk Factors for Hip Fracture in White WomenNew England Journal of Medicine, 1995