Epidemiological and Morphological Characteristics of Urothelial Bladder Cancer in a Bulgarian and a French Sample of Patients

Abstract

Bladder carcinoma (BC) is one of the most common malignancies of the urinary system in developed countries, and it is also characterized by a high number of recurrences and progression rates despite multimodal treatment. BC is a biological and clinically heterogeneous tumor with a great propensity of divergent differentiation. Around the world, bladder cancer is responsible for 549.000 new cases и 200.000 deaths each year. In Bulgaria, bladder carcinoma is the 18th most common neoplasia. Our results on 105 proven bladder carcinoma cases confirmed that this tumor arises at 70 years at average (60-90 years), it affects men predominantly and there was no difference regarding the nationality of patients. In conclusion, it remains a diagnostic challenge.