Apical sparing in tako‐tsubo cardiomyopathy
- 13 June 2006
- journal article
- Published by Wiley in Internal Medicine Journal
- Vol. 36 (7), 414-418
- https://doi.org/10.1111/j.1445-5994.2006.01095.x
Abstract
Background: Tako‐tsubo cardiomyopathy (TTC) is an acute reversible cause of segmental myocardial dysfunction that is poorly understood. We have noted a variant of this condition where a tiny segment at the apex retains some contractile function. This paper delineates the frequency of this variant relative to the classical form and the clinical differences between patients suffering from the two forms. Methods: All cases of TTC (n = 35) were identified from our infarct angiography database and separated on the basis of apical sparing (n = 14) or no apical sparing (n = 21). Results: Compared with the classical form, those with apical sparing were significantly younger (63 ± 12 vs 72 ± 13 years) and were more likely premenopausal (5/14 vs 0/21) and had higher ejection fractions (35 ± 6% vs 32 ± 4%). There was a trend towards higher recurrence (4/21 vs 0/14). There were no differences in time or season of presentation, precipitant stressor, premorbid drug therapy, haemodynamics at catheterization or acute outcomes. Conclusion: The apical sparing variant of TTC is common, accounting for 40% of cases. While the patients are younger and more likely premenopausal, there are no other distinguishing features between the classical and the variant form.Keywords
This publication has 8 references indexed in Scilit:
- Age and aneurysm position predict patterns of left ventricular dysfunction after subarachnoid hemorrhageJournal of the American Society of Echocardiography, 2005
- Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional StressNew England Journal of Medicine, 2005
- Acute and Reversible Cardiomyopathy Provoked by Stress in Women From the United StatesCirculation, 2005
- Systematic Review: Transient Left Ventricular Apical Ballooning: A Syndrome That Mimics ST-Segment Elevation Myocardial InfarctionAnnals of Internal Medicine, 2004
- Clinical characteristics and Thrombolysis In Myocardial Infarction frame counts in women with transient left ventricular apical ballooning syndromeThe American Journal of Cardiology, 2004
- Emotional Stress‐Induced Tako‐tsubo Cardiomyopathy: Animal Model and Molecular MechanismAnnals of the New York Academy of Sciences, 2004
- Tako-tsubo-like left ventricular dysfunction with ST-segment elevation: A novel cardiac syndrome mimicking acute myocardial infarctionAmerican Heart Journal, 2002
- Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarctionJournal of the American College of Cardiology, 2001