Mimics of pancreatic ductal adenocarcinoma
Open Access
- 1 January 2013
- journal article
- review article
- Published by E-MED LTD in Cancer Imaging
- Vol. 13 (3), 342-349
- https://doi.org/10.1102/1470-7330.2013.9012
Abstract
Several uncommon primary pancreatic tumors, inflammatory conditions, metastasis to the pancreas and peripancreatic masses can mimic the appearance of pancreatic ductal adenocarcinoma (PDA). Differentiation between these lesions and PDA can be challenging, due to the overlap in imaging features; however, familiarity with their typical imaging features and clinical presentation may be helpful in their differentiation, as in some cases, invasive diagnostic tests or unnecessary surgery can be avoided. The different pathologies that can mimic PDA include inflammatory conditions such as the various forms of pancreatitis (chronic-focal mass-forming, autoimmune and groove pancreatitis), pancreatic neuroendocrine tumors, solid pseudopapillary tumors, metastasis (solid non-lymphomatous and hematologic), congenital variants (annular pancreas), as well as peripancreatic lesions (accessory spleen, adrenal masses, duodenal masses, lymph nodes and vascular lesions), and certain rare pancreatic tumors (e.g., acinar cell tumors, solid serous tumors, hamartoma and solitary fibrous tumors). The clinical presentation and imaging features of the most commonly encountered mimics of PDA are discussed in this presentation with representative illustrations.Keywords
This publication has 33 references indexed in Scilit:
- CT imaging features of acinar cell carcinoma and its hepatic metastasesAbdominal Radiology, 2012
- Unusual Solid Pancreatic TumorsRadiologic Clinics of North America, 2012
- Extranodal Lymphoma From Head to Toe: Part 2, The Trunk and ExtremitiesAmerican Journal of Roentgenology, 2011
- Part 2: CT characterisation of pancreatic neoplasm: tumour mimicsInsights into Imaging, 2011
- A Focal Mass-Forming Autoimmune Pancreatitis Mimicking Pancreatic Cancer with Obstruction of the Main Pancreatic DuctJournal of Gastrointestinal Surgery, 2011
- Use of molecular targeted agents for the diagnosis, staging and therapy of neuroendocrine malignancyCancer Imaging, 2010
- A Clinical and Radiologic Review of Uncommon Types and Causes of PancreatitisRadioGraphics, 2009
- CT of Serous Cystadenoma of the Pancreas and Mimicking MassesAmerican Journal of Roentgenology, 2008
- Solid pancreatic hamartomaPathology International, 2007
- Pancreatic pseudotumors: non-neoplastic solid lesions of the pancreas that clinically mimic pancreas cancerSeminars in Diagnostic Pathology, 2004