Establishment of Inbred Strains of Chicken and Japanese Quail and their Potential as Animal Models.
- 1 January 2002
- journal article
- review article
- Published by Japanese Association for Laboratory Animal Science in Experimental Animals
- Vol. 51 (5), 417-429
- https://doi.org/10.1538/expanim.51.417
Abstract
We started establishing inbred strains of chicken and Japanese quail in 1970. In class Aves, full sib mating is highly difficult due to inbreeding depression. In the chicken, we attempted to establish some inbred strains in three breeds, Black Minorca, White Leghorn and Fayoumi by fixing all the characters that differentiate individuals homozygously. In this paper, we describe some marker genes and characters fixed in the inbred strains of chicken and Japanese quail as well as a calculation of a putative coefficient of inbreeding in 8 chicken inbred strains using band sharing values detected by AFLP analysis. We established generalized glycogenosis type II quail, myotonic dystrophy quail, neurofilament deficient quail, visually impaired chicken, double oviduct chicken with partial kidney deficiency, chicken showing spontaneous lymphocytic thyroiditis with feathered amelanosis, and chicken with a hereditary nervous disorder. The processes of establishment and characteristics of these animal models are described with some interesting information obtained from these animal models. In generalized glycogenosis type II quail, the results of enzyme replacement therapy and gene therapy are described.Keywords
This publication has 35 references indexed in Scilit:
- Neurotoxic Effects of 2,5-Hexanedione on Normal and Neurofilament-Deficient QuailToxicologic Pathology, 1999
- Adenovirus-Mediated Transfer of Human Acid Maltase Gene Reduces Glycogen Accumulation in Skeletal Muscle of Japanese Quail with Acid Maltase DeficiencyHuman Gene Therapy, 1998
- Clinical and metabolic correction of pompe disease by enzyme therapy in acid maltase-deficient quail.JCI Insight, 1998
- Molecular cloning of acid α-glucosidase cDNA of Japanese quail (Coturnix coturnix japonica) and the lack of its mRNA in acid maltase deficient quailsBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1997
- A New Inherited Muscular Disorder in Japanese Quails (Coturnix coturnix japonica)Veterinary Pathology, 1995
- Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene.The Journal of cell biology, 1993
- Japanese quail and human acid maltase deficiency: A comparative studyBrain & Development, 1991
- Mature 98,000‐dalton acid α‐glucosidase is deficient in Japanese quails with acid maltase deficiencyMuscle & Nerve, 1989
- Generalized Glycogen Storage Disease in Japanese Quail (Coturnix coturnixjaponica)Veterinary Pathology, 1983
- GENETICAL AND DEVELOPMENTAL STUDIES ON THE “Ph” AGGLUTINOGEN IN THE CHICKEN RED CELLSThe Japanese Journal of Genetics, 1975