Comprehensive Treatment of Psoriatic Arthritis: Managing Comorbidities and Extraarticular Manifestations
- 1 November 2014
- journal article
- review article
- Published by The Journal of Rheumatology in The Journal of Rheumatology
- Vol. 41 (11), 2315-2322
- https://doi.org/10.3899/jrheum.140882
Abstract
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis that can lead to decreased health-related quality of life and permanent joint damage leading to functional decline. In addition to joint and skin manifestations, both psoriasis and PsA are associated with numerous comorbidities and extraarticular/cutaneous manifestations, which may influence the physician's choice of therapy. The objectives of this review are (1) to identify comorbidities in patients with PsA based on the available evidence; (2) to examine the effects of these comorbidities or extraarticular/cutaneous manifestation on the management of patients with PsA as well as the selection of therapy; and (3) to highlight research needs around comorbidities and treatment paradigms. This review is part of a treatment recommendations update initiated by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).Keywords
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