Idpathic CD4+ T Lymphopenia in Older Persons
- 1 December 1994
- journal article
- Published by Wiley in Journal of the American Geriatrics Society
- Vol. 42 (12), 1291-1294
- https://doi.org/10.1111/j.1532-5415.1994.tb06514.x
Abstract
OBJECTIVE: Survey of the association of idiopathic CD4+T cell lymphocytopenia in older persons with protein energy undernutrition and unusual infections/colonizations. METHOD: Retrospective chart analysis. RESULTS: Five subjects aged 61 to 87 years, with unusual organisms and/or either marasmus or kwashiorkor, were noted to have absolute CD4+and CD8+T cell lymphocytopenia. All were HIV negative. CONCLUSION: T cell lymphocytopenia may not be a uncommon finding in malnourished older persons, but additional studies to determine its prevalence need to be undertaken. Its role in disease and impact on therapeutic response needs to be further explored.Keywords
This publication has 16 references indexed in Scilit:
- Idiopathic CD4+ T-Lymphocytopenia -- Four Patients with Opportunistic Infections and No Evidence of HIV InfectionNew England Journal of Medicine, 1993
- Unexplained Opportunistic Infections and CD4+ T-Lymphocytopenia without HIV Infection -- An Investigation of Cases in the United StatesNew England Journal of Medicine, 1993
- RETRACTED: Effect of vitamin and trace-element supplementation on immune responses and infection in elderly subjectsThe Lancet, 1992
- Specific nutrient abnormalities in asymptomatic HIV-1 infectionAIDS, 1992
- Nutrition in the ElderlyAnnals of Internal Medicine, 1988
- The effect of nutritional support on T-lymphocyte subpopulations in protein calorie malnutrition.Journal of the American College of Nutrition, 1986
- Nutrition and immunocompetence of the elderly: Effect of short-term nutritional supplementation on cell-mediated immunity and lymphocyte subsetsNutrition Research, 1982