Correlation between clinical/neurophysiological findings and quality of life in Charcot‐Marie‐Tooth type 1A
- 14 March 2008
- journal article
- research article
- Published by Wiley in Journal of the Peripheral Nervous System
- Vol. 13 (1), 64-70
- https://doi.org/10.1111/j.1529-8027.2008.00159.x
Abstract
Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot‐Marie‐Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot‐Marie‐Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.Keywords
This publication has 26 references indexed in Scilit:
- Electrophysiological findings in a cohort of old polio survivorsJournal of the Peripheral Nervous System, 2006
- Charcot-Marie-Tooth disease type 1A duplication with severe paresis of the proximal lower limb muscles: a long-term follow-up studyJournal of Neurology, Neurosurgery & Psychiatry, 2006
- Quality of life and disability assessment in neuropathy: a multicentre studyJournal of the Peripheral Nervous System, 2005
- The Italian SF-36 Health SurveyJournal of Clinical Epidemiology, 1998
- The phenotypic manifestations of chromosome 17p11.2 duplicationBrain, 1997
- Peripheral myelin protein 22: Facts and hypothesesJournal of Neuroscience Research, 1995
- The MOS 36-ltem Short-Form Health Survey (SF-36)Medical Care, 1992
- Human diabetic endoneurial sorbitol, fructose, and myo‐inositol related to sural nerve morphometryAnnals of Neurology, 1980
- Subjective measures of well-being.American Psychologist, 1976
- Genetic and clinical aspects of Charcot‐Marie‐Tooth's diseaseClinical Genetics, 1974