Unravelling the genetic bases of non‐target‐site‐based resistance (NTSR) to herbicides: a major challenge for weed science in the forthcoming decade
Top Cited Papers
- 15 March 2012
- journal article
- perspective
- Published by Wiley in Pest Management Science
- Vol. 69 (2), 176-187
- https://doi.org/10.1002/ps.3318
Abstract
Non-target-site-based resistance (NTSR) can confer unpredictable cross-resistance to herbicides. However, the genetic determinants of NTSR remain poorly known. The current, urgent challenge for weed scientists is thus to elucidate the bases of NTSR so that detection tools are developed, the evolution of NTSR is understood, the efficacy of the shrinking herbicide portfolio is maintained and integrated weed management strategies, including fully effective herbicide applications, are designed and implemented. In this paper, the importance of NTSR in resistance to herbicides is underlined. The most likely way in which NTSR evolves—by accumulation of different mechanisms within individual plants—is described. The NTSR mechanisms, which can interfere with herbicide penetration, translocation and accumulation at the target site, and/or protect the plant against the consequences of herbicide action, are then reviewed. NTSR is a part of the plant stress response. As such, NTSR is a dynamic process unrolling over time that involves ‘protectors’ directly interfering with herbicide action, and also regulators controlling ‘protector’ expression. NTSR is thus a quantitative trait. On this basis, a three-step procedure is proposed, based on the use of the ‘omics’ (genomics, transcriptomics, proteomics or metabolomics), to unravel the genetic bases of NTSR. Copyright © 2012 Society of Chemical IndustryKeywords
This publication has 80 references indexed in Scilit:
- Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP arrayGenomics, 2011
- Perturbations of Amino Acid Metabolism Associated with Glyphosate-Dependent Inhibition of Shikimic Acid Metabolism Affect Cellular Redox Homeostasis and Alter the Abundance of Proteins Involved in Photosynthesis and PhotorespirationPlant Physiology, 2011
- A unified approach to the estimation and interpretation of resistance costs in plantsHeredity, 2011
- Genetic control of a cytochrome P450 metabolism-based herbicide resistance mechanism in Lolium rigidumHeredity, 2010
- Rapid vacuolar sequestration: the horseweed glyphosate resistance mechanismPest Management Science, 2010
- A composite transcriptional signature differentiates responses towards closely related herbicides in Arabidopsis thaliana and Brassica napusPlant Molecular Biology, 2009
- Origin, Biogenesis, and Activity of Plant MicroRNAsCell, 2009
- Transcriptional Regulatory Networks in Response to Abiotic Stresses in Arabidopsis and GrassesPlant Physiology, 2009
- Abiotic stress response in plants: When post-transcriptional and post-translational regulations control transcriptionPlant Science, 2008
- A codon deletion confers resistance to herbicides inhibiting protoporphyrinogen oxidaseProceedings of the National Academy of Sciences of the United States of America, 2006