Tissue-based map of the human proteome
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- 23 January 2015
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 347 (6220), 1260419
- https://doi.org/10.1126/science.1260419
Abstract
Protein expression across human tissues: Sequencing the human genome gave new insights into human biology and disease. However, the ultimate goal is to understand the dynamic expression of each of the approximately 20,000 protein-coding genes and the function of each protein. Uhlén et al. now present a map of protein expression across 32 human tissues. They not only measured expression at an RNA level, but also used antibody profiling to precisely localize the corresponding proteins. An interactive website allows exploration of expression patterns across the human body. Science , this issue 10.1126/science.1260419Funding Information
- Knut and Alice Wallenberg Foundation
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