Anterior-Posterior Polarity in C. elegans and Drosophila --PARallels and Differences
- 6 December 2002
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 298 (5600), 1946-1950
- https://doi.org/10.1126/science.1072162
Abstract
The eggs of Caenorhabditis elegans and Drosophila bear little similarity to each other, yet both depend on the par genes for control of anterior-posterior polarity. Here we explore possible common roles for the par genes ( par s) in converting transient asymmetries into stably polarized axes. Although clear mechanistic parallels remain to be established, par -dependent regulation of microtubule dynamics and protein stability emerge as common themes.Keywords
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