Single cell transcriptomics comes of age
Open Access
- 27 August 2020
- journal article
- editorial
- Published by Springer Science and Business Media LLC in Nature Communications
- Vol. 11 (1), 1-4
- https://doi.org/10.1038/s41467-020-18158-5
Abstract
Single cell transcriptomics technologies have vast potential in advancing our understanding of biology and disease. Here, Sarah Aldridge and Sarah Teichmann review the last decade of technological advancements in single-cell transcriptomics and highlight some of the recent discoveries enabled by this technology.This publication has 15 references indexed in Scilit:
- A cell atlas of human thymic development defines T cell repertoire formationScience, 2020
- A cellular census of human lungs identifies novel cell states in health and in asthmaNature Medicine, 2019
- Individual brain organoids reproducibly form cell diversity of the human cerebral cortexNature, 2019
- Single-cell reconstruction of the early maternal–fetal interface in humansNature, 2018
- Spatial organization of the somatosensory cortex revealed by osmFISHNature Methods, 2018
- Single-cell transcriptomics of 20 mouse organs creates a Tabula MurisNature, 2018
- A revised airway epithelial hierarchy includes CFTR-expressing ionocytesNature, 2018
- Exponential scaling of single-cell RNA-seq in the past decadeNature Protocols, 2018
- Computational and analytical challenges in single-cell transcriptomicsNature Reviews Genetics, 2015
- mRNA-Seq whole-transcriptome analysis of a single cellNature Methods, 2009