The Clinical Pictures of Autoimmune Hemolytic Anemia
Open Access
- 1 September 2015
- journal article
- review article
- Published by S. Karger AG in Transfusion Medicine and Hemotherapy
- Vol. 42 (5), 317-324
- https://doi.org/10.1159/000440656
Abstract
Autoimmune hemolytic anemia is characterized by shortened red blood cell survival and a positive Coombs test. The responsible autoantibodies may be either warm reactive or cold reactive. The rate of hemolysis and the severity of the anemia may vary from mild to severe and life-threatening. Diagnosis is made in the laboratory by the findings of anemia, reticulocytosis, a positive Coombs test, and specific serologic tests. The prognosis is generally good but renal failure and death sometimes occur, especially in cases mediated by drugs.Keywords
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