Composite Mucoepidermoid Carcinoma and Columnar Cell Variant of Papillary Carcinoma of the Thyroid
- 10 January 2016
- journal article
- case report
- Published by SAGE Publications in International Journal of Surgical Pathology
- Vol. 24 (4), 336-340
- https://doi.org/10.1177/1066896915626281
Abstract
Primary mucoepidermoid carcinoma (MEC) of the thyroid and columnar cell variant of papillary carcinoma of the thyroid (PCT) are uncommon neoplasms. We report the first case of composite MEC and columnar cell variant of PCT. An 86-year-old man consulted for a 47-mm thyroid nodule, cytologically compatible with PCT. Total thyroidectomy was performed. Histological diagnosis, with support of histochemistry and immunohistochemistry, was mixed primary carcinoma of the thyroid, associating an MEC component with predominantly columnar cell variant of PCT. Sixteen months after surgery and external beam radiation therapy, the patient was free of recurrence or distant metastasis. This case report offers an opportunity to highlight the potential pitfalls concerning the interpretation of mucin histochemistry in thyroid tumors.Keywords
This publication has 17 references indexed in Scilit:
- Combined Papillary and Mucoepidermoid Carcinoma of the Thyroid Gland: a Possible Collision Tumor Diagnosed on Fine-Needle Cytology. Report of a Case with Immunocytochemical and Molecular CorrelationsEndocrine Pathology, 2015
- Mucoepidermoid Carcinoma of the Thyroid with Concomitant Papillary Carcinoma: Comparison of Findings on Fine-Needle Aspiration Biopsy and HistologyEndocrine Pathology, 2014
- Primary Mucoepidermoid Carcinoma of the Thyroid Gland: A Report of Three Cases and Review of the LiteratureEndocrine Pathology, 2013
- Mucoepidermoid Carcinoma of the Thyroid: A Report of Three Cases and Postulated HistogenesisThyroid®, 2012
- Clinicopathological and molecular characterization of nine cases of columnar cell variant of papillary thyroid carcinomaLaboratory Investigation, 2011
- Composite Follicular Variant of Papillary Carcinoma and Mucoepidermoid Carcinoma of Thyroid Gland: A Case ReportJournal of Korean Medical Science, 2010
- Papillary and mucoepidermoid carcinoma of the thyroid with anaplastic transformation: A case report with histologic and immunohistochemical findings that support a provocative histogenetic hypothesisPathology - Research and Practice, 1995
- Primary mucoepidermoid carcinoma of the thyroid gland: A report of six cases and a review of the literature of a follicular epithelial-derived tumorHuman Pathology, 1995
- Composite Follicular Variant of Papillary Carcinoma and Mucoepidermoid Carcinoma of the Thyroid Report of a Case and Review of the LiteratureThe American Journal of Surgical Pathology, 1995
- Mucoepidermoid carcinoma of the thyroid glandCancer, 1977