Permanent unilateral hearing loss after radiotherapy for parotid gland tumors
- 8 September 2006
- journal article
- research article
- Published by Wiley in Head & Neck
- Vol. 28 (10), 902-908
- https://doi.org/10.1002/hed.20426
Abstract
Background. The purpose of this retrospective study was to determine the long-term effects of radiotherapy on hearing function in patients who underwent parotidectomy and postoperative radiotherapy for unilateral tumors of the parotid gland. Methods. An extensive set of tests was used to measure hearing loss. The mean dose on middle ear, cochlea, and Eustachian tube was estimated with a CT-planning system. Results. A hearing loss of ≥ 15 dB in 3 frequencies was found in 32% of the 52 patients included in the study. Patients with an asymmetrical hearing loss received a higher mean dose on the hearing structures (p < .002). The threshold dose for clinically relevant hearing loss was found at 50 Gy on the cochlea and Eustachian tube. Conclusions. Radiation-induced hearing loss is a common complication. A mean dose of > 50 Gy on the cochlea should be avoided. © 2006 Wiley Periodicals, Inc. Head Neck, 2006Keywords
This publication has 15 references indexed in Scilit:
- Is sensorineural hearing loss a possible side effect of nasopharyngeal and parotid irradiation? A systematic review of the literatureRadiotherapy and Oncology, 2002
- Sensori-neural hearing loss after radiotherapy for nasopharyngeal carcinoma: individualized risk estimationRadiotherapy and Oncology, 2002
- Beam-orientation optimization of intensity-modulated radiotherapy: clinical application to parotid gland tumoursRadiotherapy and Oncology, 2001
- Radiation-Induced Hearing Impairment in Patients Treated for Malignant Parotid TumorAnnals of Otology, Rhinology & Laryngology, 1999
- Long-term sensorineural hearing deficit following radiotherapy in patients suffering from nasopharyngeal carcinoma: A prospective studyHead & Neck, 1999
- Sensorineural hearing loss in patients treated for nasopharyngeal carcinoma: A prospective study of the effect of radiation and cisplatin treatmentInternational Journal of Radiation Oncology*Biology*Physics, 1996
- Postirradiation sensorineural hearing loss: A common but ignored late radiation complicationInternational Journal of Radiation Oncology*Biology*Physics, 1996
- A prospective longitudinal study on radiation-induced hearing lossThe American Journal of Surgery, 1994
- Assessment of permanent hearing impairment following radical megavoltage radiotherapyThe Journal of Laryngology & Otology, 1988
- Sensori‐Neural hearing loss following radiotherapy to the nasopharynxThe Laryngoscope, 1976