Potato spindle tuber viroid as Inducer of RNA Silencing in Infected Tomato
Open Access
- 1 November 2001
- journal article
- research article
- Published by Scientific Societies in Molecular Plant-Microbe Interactions®
- Vol. 14 (11), 1332-1334
- https://doi.org/10.1094/mpmi.2001.14.11.1332
Abstract
Potato spindle tuber viroid (PSTVd), an RNA plant pathogen encoding no known proteins, induces systemic symptoms on tomato plants. We report detection of small RNAs of approximately 25 nucleotides with sequence specificity to PSTVd in infected plants: an indication of the presence of RNA silencing. RNA silencing, however, did not appear to be responsible for the differing symptoms induced by a mild and a severe strain of PSTVd. The unique structural and biological features of viroids make them attractive experimental tools to investigate mechanisms of RNA silencing and pathogen counterdefense.Keywords
This publication has 25 references indexed in Scilit:
- SDE3 encodes an RNA helicase required for post-transcriptional gene silencing in ArabidopsisThe EMBO Journal, 2001
- Gene silencing by double-stranded RNACurrent Opinion in Cell Biology, 2001
- Role for a bidentate ribonuclease in the initiation step of RNA interferenceNature, 2001
- RNA interference is mediated by 21- and 22-nucleotide RNAsGenes & Development, 2001
- A Calmodulin-Related Protein That Suppresses Posttranscriptional Gene Silencing in PlantsScience, 2000
- A Link Between RNA Interference and Nonsense-Mediated Decay in Caenorhabditis elegansScience, 2000
- Double-Stranded RNA as a Template for Gene SilencingCell, 2000
- Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymeraseNature, 1999
- RNA as a target and an initiator of post-transcriptional gene silencing in trangenic plantsPlant Molecular Biology, 1996
- A Replication Cycle for Viroids and Other Small Infectious RNA'sScience, 1984