Combined Approach for the Development of Efficient and Safe Nanoantimicrobials: The Case of Nanosilver-Modified Polyurethane Foams
- 28 December 2016
- journal article
- research article
- Published by American Chemical Society (ACS) in ACS Biomaterials Science & Engineering
- Vol. 3 (7), 1417-1425
- https://doi.org/10.1021/acsbiomaterials.6b00597
Abstract
Silver nanophases are routinely used as bioactive additives in commercial products. Besides their antimicrobial activity, nanosafety issues regarding the application of (silver-based) nanoantimicrobials should be considered, as well. In this study, we modified polyurethane foams, typically employed in air filtration and stuffing, by photodeposited silver nanoparticles for preparing hybrid materials (Ag-PU) with antibacterial properties. The composite materials were characterized in terms of morphology, surface chemical composition, ionic release in contact media, bioactivity, as well as whole nanoparticle release. Cytocompatibility was also assessed on 3T3 mouse fibroblasts. The proposed systematic approach allows for defining suitable composite final properties, in terms of bioactivity and safety, by properly tuning the deposition parameters.Keywords
Funding Information
- Ministero dell?Istruzione, dell?Universit? e della Ricerca (PON01_02210)
- Regione Puglia
This publication has 44 references indexed in Scilit:
- The release of silver nanoparticles from commercial toothbrushesJournal of Hazardous Materials, 2017
- Preparation and property of polyurethane/nanosilver complex fibersApplied Surface Science, 2014
- Antimicrobial, Mechanical and Thermal Studies of Silver Particle-Loaded PolyurethaneJournal of Functional Biomaterials, 2013
- Polyurethanes: Versatile Materials and Sustainable Problem Solvers for Today’s ChallengesAngewandte Chemie-International Edition, 2013
- Use of Nanosilver in Consumer ProductsRecent Patents on Nanotechnology, 2012
- Water Bactericidal Properties of Nanosilver-Polyurethane CompositesNanoscience and Nanotechnology, 2011
- Determination of engineered nanoparticles on textiles and in textile wastewatersTrAC Trends in Analytical Chemistry, 2011
- Nanosilver as a new generation of nanoproduct in biomedical applicationsTrends in Biotechnology, 2010
- The Release of Nanosilver from Consumer Products Used in the HomeJournal of Environmental Quality, 2010
- Biomedical Applications of Polyurethanes: A Review of Past Promises, Present Realities, and a Vibrant FutureJournal of Biomaterials Applications, 1999