Nucleotide sequence of a region of human mitochondrial DNA containing the precisely identified origin of replication
- 18 January 1979
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 277 (5693), 192-198
- https://doi.org/10.1038/277192a0
Abstract
A fragment of HeLa cell mitochondrial DNA containing the origin of replication has been sequenced. The precise position of the origin in this sequence has been identified by determining the nucleotide order in the 5′-end proximal portion of the heavy strand initiation fragment (7S DNA), and by aligning the two sequences.Keywords
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