Flt-1-mediated Down-regulation of Endothelial Cell Proliferation through Pertussis Toxin-sensitive G Proteins, βγ Subunits, Small GTPase CDC42, and Partly by Rac-1
Open Access
- 1 February 2002
- journal article
- Published by Elsevier BV
- Vol. 277 (6), 4003-4009
- https://doi.org/10.1074/jbc.m110842200
Abstract
No abstract availableThis publication has 36 references indexed in Scilit:
- Vascular Permeability Factor (VPF)/Vascular Endothelial Growth Factor (VEGF) Receptor-1 Down-modulates VPF/VEGF Receptor-2-mediated Endothelial Cell Proliferation, but Not Migration, through Phosphatidylinositol 3-Kinase-dependent PathwaysPublished by Elsevier BV ,2001
- Analysis of Biological Effects and Signaling Properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2)Published by Elsevier BV ,2001
- Receptor Chimeras Indicate That the Vascular Endothelial Growth Factor Receptor-1 (VEGFR-1) Modulates Mitogenic Activity of VEGFR-2 in Endothelial CellsPublished by Elsevier BV ,2000
- Vascular Endothelial Growth Factor Effect on Endothelial Cell Proliferation, Migration, and Platelet-activating Factor Synthesis Is Flk-1-dependentJournal of Biological Chemistry, 1999
- Effectors for the Rho GTPasesCurrent Opinion in Cell Biology, 1999
- A Requirement for Flk1 in Primitive and Definitive Hematopoiesis and VasculogenesisCell, 1997
- Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endotheliumNature, 1995
- Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.Proceedings of the National Academy of Sciences of the United States of America, 1993
- High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesisCell, 1993
- Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factorBiochemical and Biophysical Research Communications, 1992