Effect of Cortisone on the Permeability of the Blood-Aqueous Barrier to Fluorescein

Abstract

-Cortisone, administered by intramusc. or subconjunctival injn., does not effect the capillary permeability of the normal eye but it does reduce capillary permeability of the inflamed eye, especially when the anterior segment of the eye is involved in the inflammation. The capillary permeability was measured by assessing the rate of entry of intraven. fluorescein into the anterior chamber. It would appear that cortisone affects the capillary wall directly.