Young Zanzibari Children with Iron Deficiency, Iron Deficiency Anemia, Stunting, or Malaria Have Lower Motor Activity Scores and Spend Less Time in Locomotion , ,3
Open Access
- 1 December 2007
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Nutrition
- Vol. 137 (12), 2756-2762
- https://doi.org/10.1093/jn/137.12.2756
Abstract
Motor activity improves cognitive and social-emotional development through a child's exploration of his or her physical and social environment. This study assessed anemia, iron deficiency, hemoglobin (Hb), length-for-age Z-score (LAZ), and malaria infection as predictors of motor activity in 771 children aged 5–19 mo. Trained observers conducted 2- to 4-h observations of children's motor activity in and around their homes. Binary logistic regression assessed the predictors of any locomotion. Children who did not locomote during the observation (nonmovers) were excluded from further analyses. Linear regression evaluated the predictors of total motor activity (TMA) and time spent in locomotion for all children who locomoted during the observation combined (movers) and then separately for crawlers and walkers. Iron deficiency (77.0%), anemia (58.9%), malaria infection (33.9%), and stunting (34.6%) were prevalent. Iron deficiency with and without anemia, Hb, LAZ, and malaria infection significantly predicted TMA and locomotion in all movers. Malaria infection significantly predicted less TMA and locomotion in crawlers. In walkers, iron deficiency anemia predicted less activity and locomotion, whereas higher Hb and LAZ significantly predicted more activity and locomotion, even after controlling for attained milestone. Improvements in iron status and growth and prevention or effective treatment of malaria may improve children's motor, cognitive, and social-emotional development either directly or through improvements in motor activity. However, the relative importance of these factors is dependent on motor development, with malaria being important for the younger, less developmentally advanced children and Hb and LAZ becoming important as children begin to attain walking skills.Keywords
This publication has 32 references indexed in Scilit:
- Long-Term Impact of Malaria Chemoprophylaxis on Cognitive Abilities and Educational Attainment: Follow-Up of a Controlled TrialPLoS Clinical Trials, 2006
- Malaria, Anemia, and Malnutrition in African Children—Defining Intervention PrioritiesThe Journal of Infectious Diseases, 2006
- Long-Lasting Neural and Behavioral Effects of Iron Deficiency in InfancyPublished by Oxford University Press (OUP) ,2006
- Iron Deficiency Anemia in Infancy: Long-Lasting Effects on Auditory and Visual System FunctioningPediatric Research, 2003
- Effects of iron supplementation and anthelmintic treatment on motor and language development of preschool children in Zanzibar: double blind, placebo controlled studyBMJ, 2001
- Behaviour and Development of Stunted and Nonstunted Jamaican ChildrenJournal of Child Psychology and Psychiatry, 1999
- Activity and Behavioral Development in Stunted and Nonstunted Children and Response to Nutritional SupplementationChild Development, 1995
- Reversal of developmental delays in iron-deficient anaemic infants treated with ironThe Lancet, 1993
- Energy costs of activities of preschool childrenNutrition Research, 1983
- The effects of short-term oral iron therapy on developmental deficits in iron-deficient anemic infantsThe Journal of Pediatrics, 1982