Intramuscularly administered neuraminidase inhibitor peramivir is effective against lethal H5N1 influenza virus in mice
- 23 June 2008
- journal article
- research article
- Published by Elsevier BV in Antiviral Research
- Vol. 80 (2), 150-157
- https://doi.org/10.1016/j.antiviral.2008.05.012
Abstract
No abstract availableKeywords
This publication has 44 references indexed in Scilit:
- Efficacy and Tolerability of the Oral Neuraminidase Inhibitor Peramivir in Experimental Human Influenza: Randomized, Controlled Trials for Prophylaxis and TreatmentAntiviral Therapy, 2005
- Comparison of Efficacies of RWJ-270201, Zanamivir, and Oseltamivir against H5N1, H9N2, and Other Avian Influenza VirusesAntimicrobial Agents and Chemotherapy, 2001
- Pharmacodynamic Evaluation of RWJ-270201, a Novel Neuraminidase Inhibitor, in a Lethal Murine Model of Influenza Predicts Efficacy for Once-Daily DosingAntimicrobial Agents and Chemotherapy, 2001
- Primary immune system effects of the orally administered cyclopentane neuraminidase inhibitor RWJ-270201 in influenza virus-infected miceInternational Immunopharmacology, 2001
- Comparison of the Anti-Influenza Virus Activity of RWJ-270201 with Those of Oseltamivir and ZanamivirAntimicrobial Agents and Chemotherapy, 2001
- In Vivo Influenza Virus-Inhibitory Effects of the Cyclopentane Neuraminidase Inhibitor RWJ-270201Antimicrobial Agents and Chemotherapy, 2001
- Cyclopentane Neuraminidase Inhibitors with Potent In Vitro Anti-Influenza Virus ActivitiesAntimicrobial Agents and Chemotherapy, 2001
- The neuraminidase inhibitor GS4104 (oseltamivir phosphate) is efficacious against A/Hong Kong/156/97 (H5N1) and A/Hong Kong/1074/99 (H9N2) influenza virusesAntiviral Research, 2000
- In vitro and in vivo assay systems for study of influenza virus inhibitorsAntiviral Research, 2000
- BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug DesignJournal of Medicinal Chemistry, 2000