Genome Analysis Reveals Pili in Group B Streptococcus
- 1 July 2005
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 309 (5731), 105
- https://doi.org/10.1126/science.1111563
Abstract
Pili are essential virulence factors in many Gram-negative bacteria; however, they have not been described in most important Gram-positive pathogens. While screening the sequence of multiple genomes of Group B Streptococcus , we identified protective antigens that formed high molecular weight polymers. Immunogold electron microscopy revealed that the structures have a pilus-like form. These large structures have gone unrecognized in decades of studies of Group B Streptococcus .Keywords
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