Hit and lead identification: Integrated technology-based approaches
- 28 February 2007
- journal article
- review article
- Published by Elsevier BV in Drug Discovery Today: Technologies
- Vol. 3 (4), 367-375
- https://doi.org/10.1016/j.ddtec.2006.12.009
Abstract
No abstract availableThis publication has 43 references indexed in Scilit:
- Application of Laser-Scanning Fluorescence Microplate Cytometry in High Content ScreeningASSAY and Drug Development Technologies, 2006
- Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cellsJournal of Lipid Research, 2006
- Recent applications of protein crystallography and structure-guided drug designCurrent Opinion in Chemical Biology, 2005
- Fragonomics: fragment-based drug discoveryCurrent Opinion in Chemical Biology, 2005
- Integration of Virtual Screening with High-Throughput Flow Cytometry to Identify Novel Small Molecule Formylpeptide Receptor AntagonistsMolecular Pharmacology, 2005
- Convergent Diversity-Oriented Synthesis of Small-Molecule HybridsAngewandte Chemie, 2005
- Structural Determinants of CDK4 Inhibition and Design of Selective ATP Competitive InhibitorsCell Chemical Biology, 2004
- β-Alanine dipeptides as MC4R agonistsBioorganic & Medicinal Chemistry Letters, 2003
- Natural Products as Sources of New Drugs over the Period 1981−2002Journal of Natural Products, 2003
- From the combinatorial chemistry boom to polymer-supported parallel chemistry: established technologies for drug discoveryDrugs of the Future, 2003