Merging Oxidative Dearomatization and Aminocatalysis: One-Pot Enantioselective Synthesis of Tricyclic Architectures
- 28 October 2013
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 15 (22), 5642-5645
- https://doi.org/10.1021/ol402546h
Abstract
The combination of oxidative dearomatization and trienamine/enamine activation in a single vessel is described. Under these conditions, a three-bond forming process generates functionalized tricyclic architectures with up to six contiguous stereocenters with excellent stereoselectivities from readily available planar substrates.Keywords
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