Deterioration of Myocardial Function Following Aorto-Coronary Bypass Operation
- 1 March 1974
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 49 (3), 467-475
- https://doi.org/10.1161/01.cir.49.3.467
Abstract
Twenty-two patients underwent cardiac catheterization before and an average of five months after aorto-coronary bypass operation (ACBO). Two groups were examined: 10 patients with all grafts patent, and 12 patients with one or more grafts occluded. All patients improved symptomatically, regardless of graft patency. However, in the occluded group, left ventricular end-diastolic pressure (LVEDP) increased (4.4 ± 2.2 mm Hg, P < 0.05), stroke volume index fell (9.8 ± 3.1 ml/m 2 , P < 0.05), ejection fraction decreased (10 ± 4%, P < 0.05), and left ventricular stroke work index fell (12 ± 3 g-m/m 2 , P < 0.01). Qualitative analysis of segmental left ventricular contractility was performed. Of 28 segments supplied by patent grafts, six improved and nine deteriorated. Of 22 segments supplied by occluded grafts, none improved and eight deteriorated. Frequently no angiographically demonstrable basis for the segmental deterioration was evident. We concluded that while ACBO may appreciably benefit severely symptomatic patients, our results do not substantiate the claim that ACBO should be recommended when the primary surgical goal is preservation or enhancement of myocardial function.This publication has 8 references indexed in Scilit:
- Depression of Left Ventricular Function Due to Acute Myocardial Ischemia and Its Reversal after Aortocoronary Saphenous-Vein BypassThe New England Journal of Medicine, 1972
- Survival experience in saphenous vein bypass graft surgeryThe American Journal of Cardiology, 1972
- Follow-up results of distal coronary artery bypass for ischemic heart diseaseThe American Journal of Cardiology, 1972
- Ischemic myocardial injury during coronary artery surgeryAmerican Heart Journal, 1971
- Bypass Grafting for Occlusive Disease of the Coronary ArteriesAnnals of Surgery, 1971
- Ascending aorta-to-coronary artery saphenous vein bypass graftsThe Journal of Thoracic and Cardiovascular Surgery, 1970
- Left ventricular volume and mass from single-plane cineangiocardiogram. A comparison of anteroposterior and right anterior oblique methodsAmerican Heart Journal, 1970