Rapid multiexposure in vivo brain imaging system using vertical cavity surface emitting lasers as a light source
- 11 February 2013
- journal article
- Published by Optica Publishing Group in Applied Optics
- Vol. 52 (7), C64-C71
- https://doi.org/10.1364/ao.52.000c64
Abstract
We demonstrate an imaging technique implementing vertical cavity lasers with extremely low transient times for a greatly simplified realization of a multiexposure laser speckle contrast imaging system. Data from multiexposure laser speckle imaging was observed to more closely agree with absolute velocity measurements using time of flight technique, when compared to long-exposure laser speckle imaging. Furthermore, additional depth information of the vasculature morphology was inferred by accounting for the change in the static scattering from tissue above vessels with respect to the total scattering from blood flow and tissue.Funding Information
- Natural Sciences and Engineering Research Council of Canada (RGPIN-355623-08)
- Collaborative Health Research Project (CPG-121050)
- Networks of Centres of Excellence of Canada
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