AN ANALYSIS OF EXTRACELLULAR POTENTIALS FROM SINGLE NEURONS IN THE LATERAL GENICULATE NUCLEUS OF THE CAT
Open Access
- 20 January 1958
- journal article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 41 (3), 543-564
- https://doi.org/10.1085/jgp.41.3.543
Abstract
The lateral geniculate nucleus of the cat was explored with micropipettes having submicroscopic tips. The only reliably recorded intracellular activity was from axons. Following orthodromic stimulation, the potentials recorded by the extracellular electrodes registered the net flow of current across the soma-dendritic membrane of the principal cell bodies. The current has three phases of flow away from the soma-dendritic membrane followed by a flow of current toward this membrane. The first component is ascribed to synaptic activity. Subsequent components are ascribed to the activity of the initial segment of the axon and a limited area of high threshold membrane on the soma. The evidence is interpreted as suggesting that most of the soma-dendritic membrane is excited synaptically to produce a postsynaptic potential, but is not excited electrically and does not produce a propagating spike.Keywords
This publication has 23 references indexed in Scilit:
- Electrical Inexcitability of Synapses and Some Consequences in the Central Nervous SystemPhysiological Reviews, 1957
- CORTICAL MOTOR THRESHOLD AND THE THRESHOLDS AND DISTRIBUTION OF EXCITED BETZ CELLS IN THE CATQuarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1956
- INITIATION AND ABOLITION OF THE ACTION POTENTIAL OF A SINGLE NODE OF RANVIERThe Journal of general physiology, 1956
- Potentials recorded from the spinal cord with microelectrodesThe Journal of Physiology, 1955
- Activity of single neurons in the tactile thalamic region of the cat in response to a transient peripheral stimulus.1954
- Synaptic transmission. An analysis of the electrical activity of the lateral geniculate nucleus in the cat after optic nerve stimulationProceedings of the Royal Society of London. Series B - Biological Sciences, 1953
- PHENOMENON OF REPETITIVE FIRING IN LATERAL GENICULATE OF CATJournal of Neurophysiology, 1953
- Spontaneous subthreshold activity at motor nerve endings.1952
- CORTICAL NEURONS WITH PARTICULAR REFERENCE TO THE APICAL DENDRITESPublished by Cold Spring Harbor Laboratory ,1952
- The termination of optic fibres in the lateral geniculate body of the monkey.1941