N-Acylsulfonamide Assisted Tandem C−H Olefination/Annulation: Synthesis of Isoindolinones
- 8 February 2011
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 13 (5), 1214-1217
- https://doi.org/10.1021/ol200093f
Abstract
A tandem C−H olefination/annulation sequence directed by N-acylsulfonamides affords a variety of isoindolinones. This transformation is compatible with aliphatic alkenes as well as conjugated alkenes. Notably, molecular oxygen can be used as the sole, eco-friendly oxidant.Keywords
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