The Pulmonary Response of White and Black Adults to Six Concentrations of Ozone
- 1 April 1993
- journal article
- research article
- Published by American Thoracic Society in American Review of Respiratory Disease
- Vol. 147 (4), 804-810
- https://doi.org/10.1164/ajrccm/147.4.804
Abstract
Many early studies of respiratory responsiveness to ozone (O3) were done on healthy, young, white males. The purpose of this study was to determine whether gender or race differences in O3 response exist among white and black, males and females, and to develop concentration-response curves for each of the gender-race groups. Three hundred seventy-two subjects (n > 90 in each gender-race group), ages 18 to 35 yr, were exposed once for 2.33 h to 0.0 (purified air), 0.12, 0.18, 0.24, 0.30, or 0.40 ppm O3. Each exposure was preceded by baseline pulmonary function tests and a symptom questionnaire. The first 2 h of exposure included alternating 15-min periods of rest and exercise on a motorized treadmill producing a minute ventilation (VE) of 25 L/min/m2 body surface area (BSA). After exposure, subjects completed a set of pulmonary function tests and a symptom questionnaire. Lung function and symptom responses were expressed as percent change from baseline and analyzed using a nonparametric two factor analysis of variance. Three primary variables were analyzed: FEV1, specific airway resistance (SRaw), and cough. Statistical analysis demonstrated no significant differences in response to O3 among the individual gender-race groups. For the group as a whole, changes in the variables FEV1, SRaw, and cough were first noted at 0.12, 0.18, and 0.18 ppm O3, respectively. Adjusted for exercise difference, concentration-response curves for FEV1 and cough among white males were consistent with previous reports (1).Keywords
This publication has 11 references indexed in Scilit:
- Ozone inhalation effects in females varying widely in lung size: comparison with malesJournal of Applied Physiology, 1990
- The elastic field associated with a square dislocation loop in a two-phase mediumJournal of Applied Physics, 1987
- Ozone inhalation effects consequent to continuous exercise in females: comparison to malesJournal of Applied Physiology, 1985
- Pulmonary effects of ozone exposure during exercise: dose-response characteristicsJournal of Applied Physiology, 1983
- Design and performance of a system to control concentrations of common gaseous air pollutants within environmental laboratories used for human exposure studiesJournal of Environmental Science and Health . Part A: Environmental Science and Engineering, 1981
- Stepwise Multiple Comparison ProceduresJournal of the American Statistical Association, 1977
- Significance tests for multiple comparison of proportions, variances, and other statistics.Psychological Bulletin, 1960
- Multiple comparison in psychological research.Psychological Bulletin, 1959
- A NEW METHOD FOR MEASURING AIRWAY RESISTANCE IN MAN USING A BODY PLETHYSMOGRAPH: VALUES IN NORMAL SUBJECTS AND IN PATIENTS WITH RESPIRATORY DISEASE 1JCI Insight, 1956
- VITAL CAPACITY OF NEGRO RACEPublished by American Medical Association (AMA) ,1926