Evaluating a native collagen matrix dressing in the treatment of chronic wounds of different aetiologies: a case series
- 2 November 2016
- journal article
- research article
- Published by Mark Allen Group in Journal of Wound Care
- Vol. 25 (11), 670-678
- https://doi.org/10.12968/jowc.2016.25.11.670
Abstract
Objective: To collate clinical evidence on the use of a native collagen matrix dressing, consisting of a fibrillary collagen network, in patients with a variety of chronic wounds. Method: Patients whose wounds had not improved in the eight weeks before the beginning of the evalutaion were recruited. All participants had their dressings changed twice weekly and received standard adjunctive wound care as part of their treatment. Data, collected over a 4-week period, included: patient demographics, wound surface area measurements, Bates-Jensen score, level of wound pain, wound infection status, wound bed preparation staging score, depth of wound according to tissue type, and photographic imaging of patients' wounds. Results: We recruited 19 patients with 20 wounds and a mean wound duration of 66.6 months (range: 4–480 months). There was a mean decrease in wound surface area of 29% (median reduction: 47%). A reduction in the Bates-Jensen score was demonstrated in 85% of cases. Wound pain reduced by 66.66% and the wound bed preparation score reduced in 16 wounds with four remaining static. No adverse events arose. Conclusion: This case series provides clinical evidence on the use of a native collagen matrix dressing in the management of hard-to-heal wounds that have previously received local standard therapy. The decrease in wound surface area together with other data indicating improved wound status suggests that a native collagen matrix dressing supports healing and improves quality of life through reduction in wound pain.Keywords
This publication has 18 references indexed in Scilit:
- Predictors of Lower-Extremity Amputation in Patients With an Infected Diabetic Foot UlcerDiabetes Care, 2015
- Collagen matrix wound dressings and the treatment of DFUsJournal of Wound Care, 2013
- Quality of Life with Diabetes-associated Foot Complications: Comparison Between Lower-limb Amputation and Chronic Foot UlcerationFoot & Ankle International, 2008
- Multimorbidity and quality of life: a closer lookHealth and Quality of Life Outcomes, 2007
- Cumulative Illness Rating Scale was a reliable and valid index in a family practice contextJournal of Clinical Epidemiology, 2005
- Effect of collagen matrices on dermal wound healingAdvanced Drug Delivery Reviews, 2003
- Wound bed preparation: a systematic approach to wound managementWound Repair and Regeneration, 2003
- Classifications for wound bed preparation and stimulation of chronic woundsWound Repair and Regeneration, 2000
- The fate of collagen implants in tissue defectsWound Repair and Regeneration, 2000
- Prospective, Multicenter Study of Managing Lower Extremity Venous UlcersAnnals of Vascular Surgery, 1994