Solid pseudopapillary neoplasms of the pancreas: An updated experience
- 3 May 2007
- journal article
- research article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 95 (8), 640-644
- https://doi.org/10.1002/jso.20735
Abstract
Introduction The aim of this study is to report an update of the surgical experience at a single institution with these unusual tumors. Methods Sixteen consecutive patients who underwent surgery for a pathologically confirmed solid pseudopapillary neoplasm (SPPN) were retrospectively reviewed. Results Fifteen of the patients were female and the median age at diagnosis was 30 years (range, 14–53 years). Abdominal and back pain were the most common presenting symptoms. The tumors appeared on cross-sectional imaging as solid and cystic (n = 14) or cystic (n = 2) masses. The median tumor size was 9.5 cm (range, 5.0–24.0 cm). All 16 patients had curative resections including 3 pancreaticoduodenectomies and 13 distal pancreatectomies. Three patients required extended resections including pancreaticoduodenectomy with portal vein resection, distal pancreatectomy with tranverse colectomy, and distal pancreactomy with omentectomy. Two of the resections were R1 whereas 14 were R0. All patients were alive and disease-free at a median follow-up of 43 months (range, 3–186 months). Conclusion SPPNs should be considered in young women presenting with a large solid-cystic pancreatic mass. Aggressive en bloc resection should always be attempted including resection of concomitant metastases as patients demonstrate excellent long-term survival even in the presence of distant spread. J. Surg. Oncol. 2007;95:640–644.Keywords
This publication has 12 references indexed in Scilit:
- Cystic lesions of the pancreas: an appraisal of an aggressive resectional policy adopted at a single institution during 15 yearsThe American Journal of Surgery, 2006
- The Solid-Pseudopapillary Tumor of Pancreas: The Clinical Characteristics and Surgical TreatmentJournal of Surgical Research, 2006
- Malignant potential of solid pseudopapillary neoplasm of the pancreasBritish Journal of Surgery, 2006
- Solid‐pseudopapillary tumours of the pancreas: 14 years experienceAnz Journal of Surgery, 2005
- Solid Pseudopapillary Tumors of the Pancreas: Review of 718 Patients Reported in English LiteratureJournal of the American College of Surgeons, 2005
- Solid pseudopapillary neoplasms of the pancreas: Is there a pathologic basis for the observed gender differences in incidence?Surgery, 2005
- Clinically Aggressive Solid Pseudopapillary Tumors of the PancreasThe American Journal of Surgical Pathology, 2005
- Management of a solid pseudopapillary tumor of the pancreas with liver metastasesHPB, 2003
- Solid pseudopapillary tumour of the pancreasAnz Journal of Surgery, 2003
- Solid-pseudopapillary tumor of the pancreas: A surgical enigma?Annals of Surgical Oncology, 2002