Aerosol emission and superemission during human speech increase with voice loudness
Top Cited Papers
Open Access
- 20 February 2019
- journal article
- research article
- Published by Springer Science and Business Media LLC in Scientific Reports
- Vol. 9 (1), 1-10
- https://doi.org/10.1038/s41598-019-38808-z
Abstract
Mechanistic hypotheses about airborne infectious disease transmission have traditionally emphasized the role of coughing and sneezing, which are dramatic expiratory events that yield both easily visible droplets and large quantities of particles too small to see by eye. Nonetheless, it has long been known that normal speech also yields large quantities of particles that are too small to see by eye, but are large enough to carry a variety of communicable respiratory pathogens. Here we show that the rate of particle emission during normal human speech is positively correlated with the loudness (amplitude) of vocalization, ranging from approximately 1 to 50 particles per second (0.06 to 3 particles per cm3) for low to high amplitudes, regardless of the language spoken (English, Spanish, Mandarin, or Arabic). Furthermore, a small fraction of individuals behaves as “speech superemitters,” consistently releasing an order of magnitude more particles than their peers. Our data demonstrate that the phenomenon of speech superemission cannot be fully explained either by the phonic structures or the amplitude of the speech. These results suggest that other unknown physiological factors, varying dramatically among individuals, could affect the probability of respiratory infectious disease transmission, and also help explain the existence of superspreaders who are disproportionately responsible for outbreaks of airborne infectious disease.Keywords
Funding Information
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases (R01 AI110703, R01 AI110703, R01 AI110703, R01 AI110703, R01 AI110703, R01 AI110703)
This publication has 52 references indexed in Scilit:
- Cough aerosol in healthy participants: fundamental knowledge to optimize droplet-spread infectious respiratory disease managementBMC Pulmonary Medicine, 2012
- Electron cryotomography of measles virus reveals how matrix protein coats the ribonucleocapsid within intact virionsProceedings of the National Academy of Sciences of the United States of America, 2011
- Seasonal and Pandemic Human Influenza Viruses Attach Better to Human Upper Respiratory Tract Epithelium than Avian Influenza VirusesThe American Journal of Pathology, 2010
- Exhaled droplets due to talking and coughingJournal of The Royal Society Interface, 2009
- Aerosol transmission of influenza A virus: a review of new studiesJournal of The Royal Society Interface, 2009
- Absolute humidity modulates influenza survival, transmission, and seasonalityProceedings of the National Academy of Sciences of the United States of America, 2009
- Inactivation of influenza A viruses in the environment and modes of transmission: A critical reviewJournal of Infection, 2008
- Influenza Virus in Human Exhaled Breath: An Observational StudyPLOS ONE, 2008
- Human and Avian Influenza Viruses Target Different Cells in the Lower Respiratory Tract of Humans and Other MammalsThe American Journal of Pathology, 2007
- Review of Aerosol Transmission of Influenza A VirusEmerging Infectious Diseases, 2006