The specificity of serum prolactin as a diagnostic indicator of pituitary adenoma
- 1 July 1979
- journal article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 51 (1), 42-46
- https://doi.org/10.3171/jns.1979.51.1.0042
Abstract
Serum prolactin levels were determined in 205 patients with a variety of intracranial diseases, including 70 cases with pituitary tumors. It is concluded that although the absence of elevated prolactin levels does not help to rule out pituitary pathology, the presence of hyperprolactinemia is highly specific for diseases of the pituitary and hypothalamus, and prolactin determination should be part of the regular work-up of pituitary tumor suspects. Excluding known causes of hyperprolactinemia, such as tranquilizing drug ingestion, the presence of neurological disease outside the hypothalamic-pituitary area was not associated with increased serum prolactin concentrations.Keywords
This publication has 8 references indexed in Scilit:
- ProlactinThe New England Journal of Medicine, 1978
- Prolactin‐Secreting pituitary tumorsAnnals of Neurology, 1977
- PREVALENCE AND PRESENTATION OF HYPERPROLACTINÆMIA IN PATIENTS WITH "FUNCTIONLESS" PITUITARY TUMOURSThe Lancet, 1977
- Galactorrhea: A Study of 235 Cases, Including 48 with Pituitary TumorsThe New England Journal of Medicine, 1977
- The Assay and Regulation of Prolactin in HumansAdvances in Experimental Medicine and Biology, 1977
- Surgical Problems of Pituitary AdenomasAdvances and Technical Standards in Neurosurgery, 1976
- Endocrine Manifestations of Intracranial Extrasellar LesionsJournal of Clinical Endocrinology & Metabolism, 1962
- Intrasellar Aneurysms Simulating Hypophyseal TumoursJournal of Neurosurgery, 1961